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Sildenafil and/or N-desmethylsildenafil, its major active metabolite, may be quantified in plasma, serum, or whole blood to assess pharmacokinetic status in those receiving the drug therapeutically, to confirm the diagnosis in potential poisoning victims, or to assist in the forensic investigation in a case of fatal overdose. A tet-regulated transcription unit can further be incorporated into a recombinant vector (e.g., provera 10mg webmd a plasmid or viral vector) by standard recombinant DNA techniques.

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